Researchers have developed a method that could make magnetic resonance imaging – MRI – multicolour and help improve disease diagnosis.Current MRI techniques rely on a single contrast agent injected into a patient\u2019s veins to vivify images.<\/p>\n
The new method uses two at once, which could allow doctors to map multiple characteristics of a patient\u2019s internal organs in a single MRI. The strategy could serve as a research tool and even aid disease diagnosis.<\/p>\n
\u201cThe method we developed enables, for the first time, the simultaneous detection of two different MRI contrast agents,\u201d said Chris Flask, Associate Professor at Case Western Reserve University School of Medicine in Cleveland, Ohio, US.<\/p>\n
Two contrast agents could include one specifically targeting diseased tissue, and one designed to show healthy tissue, for example. The new method would enable immediate comparisons of how each agent distributes in the same patient.<\/p>\n
\u201cThis multi-agent detection capability has the potential to transform molecular imaging, as it provides a critical translational pathway for studies in patients,\u201d said Flask.<\/p>\n
In a study published in the journal Scientific Reports, the researchers described how two contrast agents, gadolinium and manganese, can be detected and independently quantified during MRIs.<\/p>\n
The results provide \u201can adaptable, quantitative imaging framework to assess two MRI contrast agents simultaneously for a wide variety of imaging applications\u201d, the researchers said.<\/p>\n
\u201cIn this initial paper, we validated our new methodology, opening the possibility for numerous follow-on application studies in cancer, genetic diseases such as cystic fibrosis, and metabolic diseases such as diabetes,\u201d Flask said.<\/p>\n
IANS<\/p>\n
Picture: Alamy<\/p>\n
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